Investigador responsable: Ana María Avellón Calvo
. aavellon@isciii.es
Entidad: Instituto de Salud Carlos III. CNM
Investigadores:
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Desarrollo y evaluación de tecnología. |
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Secuenciación masiva. |
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Epidemiología molecular. |
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Análisis de mutaciones. |
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Metagenómica hepatitis agudas de etiología desconocida |
PROYECTO GILEAD 2023: Characterizing hepatitis delta virus in Spain from 2012 to 2022 by means of new developed techniques (IP Ana Avellón) 2024-2025
PROYECTO CIBERESP 2022 MICROBIOLOGICAL AND GENOMIC INVESTIGATION OF HEPATITIS IN CHILDREN BY METAGENOMIC APPROACH IN CASE AND CONTROL SUBJECTS (IP: Ana Avellón. Co IP Desiré Henares). 2023-2024
TRAZABILIDAD DE LA INFECCIÓN POR EL VIRUS DE LA HEPATITIS E MEDIANTE ESTUDIO EPIDEMIOLÓGICO Y DE SECUENCIAS COMPLETAS VIRALES.- TRAZHE: Programa de investigación intramural ISCIII 2019. MPY 501-19: (IP: Ana Avellón). 2020-2024.
CONTRATO DE INVESTIGACIÓN ENTRE EL INSTITUTO DE SALUD CARLOS III O.A., M.P. Y DIASORIN IBERIA S.A. PARA EL DESARROLLO DEL ESTUDIO: "EVALUACIÓN TÉCNICA DE UN NUEVO ENSAYO DE QUIMIOLUMINISCENCIA PARA LA DETECCIÓN DE ANTICUERPOS ANTI VIRUS DE LA HEPATITIS E. (IP Ana Avellón)
1: Muñoz-Chimeno M, Valencia J, Rodriguez-Recio A, Cuevas G, Garcia-Lugo A, Manzano S, Rodriguez-Paredes V, Fernandez B, Morago L, Casado C, Avellón A. HCV, HIV AND HBV rapid test diagnosis in non-clinical outreach settings can be as accurate as conventional laboratory tests. Ryan P.Sci Rep. 2023 May 9;13(1):7554. doi: 10.1038/s41598-023-33925-2.
2: Guerrero-Vadillo M, Peñuelas M, Domínguez Á, Godoy P, Gómez-Barroso D, Soldevila N, Izquierdo C, Martínez A, Torner N, Avellón A, Rius C, Varela C. Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak. Int J Environ Res Public Health. 2022 Dec 14;19(24):16775. doi: 10.3390/ijerph192416775.
3: Muñoz-Chimeno M, Rodriguez-Paredes V, García-Lugo MA, Avellon A. Hepatitis E genotype 3 genome: A comprehensive analysis of entropy, motif conservation, relevant mutations, and clade-associated polymorphisms. Front Microbiol. 2022 Oct 6;13:1011662.
4: Romaní Vidal A, Vaughan A, Innocenti F, Colombe S, Nerlander L, Rachwal N, Ciancio BC, Mougkou A, Carvalho C, Delgado E, Mook P, de Muylder G, Peeters M, Tenev T, Golkocheva-Markova E, Vorobieva Solholm Jensen V, Koch A, Figoni J, Brouard C, Nikolopoulou G, Zisouli A, Murphy N, Broderick A, Goldberg L, Rich R, Hecht Sagie L, Tosti ME, Suligoi B, Joosten R, Pijnacker R, Fjeldheim I, Heen E, Stępień M, Polański P, Tato Marinho R, Vieira Martins J, Varela C, Avellón A, Andersson E, Jansson Mörk M, Mandal S, Watson C, Coughlan L, Chand M, Neill C, Bradley DT, Li K, O'Leary M, McInnes N, Williams CJ, Moore C, Gjini A, Duffell E, Pebody R. Hepatitis of unknown aetiology in children – epidemiological overview of cases reported in Europe, 1 January to 16 June 2022. Euro Surveill. 2022 Aug;27(31):2200483.
5: Simões D, Ehsani S, Stanojevic M, Shubladze N, Kalmambetova G, Paredes R, Cirillo DM, Avellon A, Felker I, Maurer FP, Yedilbayev A, Drobniewski F, Vojnov L, Johansen AS, Seguy N, Dara M; European Laboratory Initiative on TB, HIV and viral hepatitis core group members. Integrated use of laboratory services for multiple infectious diseases in the WHO European Region during the COVID-19 pandemic and beyond. Euro Surveill. 2022 Jul;27(29):2100930.
6: Muñoz-Chimeno M, Bartúren S, García-Lugo MA, Morago L, Rodríguez Á, Galán JC, Pérez-Rivilla A, Rodríguez M, Millán R, Del Álamo M, Alonso R, Molina L, Aguinaga A, Avellón A. Hepatitis E virus genotype 3 microbiological surveillance by the Spanish Reference Laboratory: geographic distribution and phylogenetic analysis of subtypes from 2009 to 2019. Euro Surveill. 2022 Jun;27(23):2100542.
7: Domínguez A, Varela C, Soldevila N, Izquierdo C, Guerrero M, Peñuelas M, Martínez A, Godoy P, Borràs E, Rius C, Torner N, Avellón AM, Castilla J, Previcet Working Group On Viral Hepatitis. Hepatitis A Outbreak Characteristics: A Comparison of Regions with Different Vaccination Strategies, Spain 2010-2018. Vaccines (Basel). 2021 Oct 20;9(11):1214.
8: Estirado Gómez A, Justo Gil S, Limia A, Avellón A, Arce Arnáez A, González- Rubio R, Diaz A, Del Amo J; Working group of the HCV prevalence study in Spain in 2017–2018. Prevalence and undiagnosed fraction of hepatitis C infection in 2018 in Spain: results from a national population-based survey. Eur J Public Health. 2021 Dec 1;31(6):1117-1122.
9: Muñoz-Chimeno M, Cenalmor A, Garcia-Lugo MA, Hernandez M, Rodriguez-Lazaro D, Avellon A. Proline-Rich Hypervariable Region of Hepatitis E Virus: Arranging the Disorder. Microorganisms. 2020 Sep 15;8(9):1417. 9: Avellon A, Ala A, Diaz A, Domingo D, Gonzalez R, Hidalgo L, Kooner P, Loganathan S, Martin D, McPherson S, Munoz-Chimeno M, Ryder S, Slapak G, Ryan P, Valbuena M, Kennedy PT. Clinical performance of Determine HBsAg 2 rapid test for Hepatitis B detection. J Med Virol. 2020 Apr 9.
10: García N, Hernández M, Gutierrez-Boada M, Valero A, Navarro A, Muñoz-Chimeno M, Fernández-Manzano A, Escobar FM, Martínez I, Bárcena C, González S, Avellón A, Eiros JM, Fongaro G, Domínguez L, Goyache J, Rodríguez-Lázaro D. Occurrence of Hepatitis E Virus in Pigs and Pork Cuts and Organs at the Time of Slaughter, Spain, 2017. Front Microbiol. 2020 Jan 28;10:2990.
